Pair Name	Carnosic acid, Cisplatin
Disease Info	[ICD-11: 2C25.Z]	Lung cancer		Investigative
Gene Regulation	Up-regulation	Expression	CD8A	hsa925
	Up-regulation	Expression	IFNG	hsa3458
	Up-regulation	Expression	FASLG	hsa356
	Up-regulation	Expression	PRF1	hsa5551
	Up-regulation	Expression	GZMB	hsa3002
	Down-regulation	Expression	ARG1	hsa383
	Down-regulation	Expression	MMP9	hsa4318
In Vitro Model	A9 [Mouse Lewis lung carcinoma]	Malignant tumors of the mouse pulmonary system	Mus musculus (Mouse)	CVCL_S007
In Vivo Model	Mouse LLC (Lewis lung cancer) cells (5×10⁶ cells in 0.1 mL) were injected into the right flank of C57BL/6 mice.
Result	Our study proved that the functional suppression of MDSC by carnosic acid promoted the lethality of CD8 T cells, which contributed to the enhancement of anti-lung cancer effect of cisplatin.